Sildenafil (Oral Tablet): Side Effects, Dosage, and Uses

Many worldwide manufacturers now provide sildenafil, the medication’s brand name, as a generic version. Viagra, the first significant erectile dysfunction (ED) drug on the market and a product of Pfizer, is essentially the same drug as sildenafil.

The existence of generic Viagra is relatively recent. Even though Pfizer’s patent on the well-known ED drug expired in 2020, Pfizer began producing and marketing generic sildenafil in 2017. The possibilities for customers immediately grew as other businesses were authorized to offer their sildenafil pills lawfully in 2020.

Why is it Used?

The most popular use of sildenafil is as a remedy for ED,or the inability to get or maintain an erection. However, knowing that sildenafil’s effects will wear off after a few hours, it is recommended that you take it before sex.

Additionally, pulmonary hypertension (PH), or high blood pressure in the arteries of the lungs and the right side of the heart, is treatable with sildenafil. Sildenafil is marketed under the name Revatio and is used to treat PH.

Sildenafil is always offered under the sildenafil brand name.

unluckily aside from Viagra and Revatio, there aren’t any other brand names for the medication.

Dosage of Viagra

Sildenafil, the active ingredient in generic Viagra, comes in doses of 20 mg, 25 mg, 50 mg, and 100 mg tablets and liquid. Typically, it is taken three times daily. The recommended dosage is 50 mg. However, your doctor may advise you to start on 25 mg to gauge your response.

Mechanism of Action

An oral treatment for erectile dysfunction is sildenafil 5,12,13,16,8. It improves erectile dysfunction by boosting blood flow to the penis when used in a realistic situation, such as during sexual stimulation 5,12,13,16,8.

Nitric oxide (NO) is released in the corpus cavernosum during sexual stimulation, which is the physiological mechanism for the erection of the penis 5,12,13,16,8. In turn, cyclic guanosine monophosphate (cGMP) levels rise due to nitric oxide activating the enzyme guanylate cyclase, causing the smooth muscle in the corpus cavernosum to relax and enabling blood to enter 5,12,13,16,8.

The corpus cavernosum’s phosphodiesterase type 5 (PDE5), which is in charge of degrading cGMP 5,12,13,16,8, is precisely and powerfully inhibited by sildenafil. Sildenafil acts on erections 5, 12, 13, 16, and 8 at a peripheral location. On an isolated human corpus cavernosum, sildenafil has no direct relaxing effects, but it significantly boosts the relaxing effects of NO on this tissue (5,12,13,16,8). Increased amounts of cGMP 5,12,13,16,8 are produced in the corpus cavernosum due to sildenafil’s inhibition of PDE5, which happens when the NO/cGMP pathway is active, as it is during sexual stimulation. Therefore, sildenafil has to be taken with sexual excitement to have the positive pharmacological effects that are intended 5,12,13,16,8.

Side Effects

There might be nausea, flushing, headaches, or dizziness. Changes in eyesight might also include heightened sensitivity to light, blurred vision, or difficulty identifying blue from green. If these side effects continue or worsen, meet your physician.

When getting out of a sitting or lying posture, take it gently to lessen the chance of feeling lightheaded and dizzy.

Remember that your doctor has recommended this medicine because they believe it will help you more than harm you. Many users of this medicine report no significant negative effects.

Why Buy Adderall Medicine Online?

For some people, purchasing prescription medications online provides benefits not accessible at a local pharmacy, such as:

• Medicines are more readily available for persons confined to their houses or who live far from a pharmacy.
• Written product information and references are more easily accessible than in traditional retail pharmacies.
• The opportunity to place orders and speak with a pharmacist from the comfort of your own home.
• Consumers also save money by shopping for medicines over the internet. This is true in certain circumstances.